Ulcerative Colitis Regions

AS ATD CEL CRO JIA MS PBC PSO RA SLE T1D UC

A table of Human loci associated with Ulcerative Colitis. Cytogenetic bands are defined using data from UCSC genome browser, protein coding and non-coding genes were extracted from EnsEMBL v84. Hits were defined by taking the index variant as described in the listed publication. Starting at the variant of interest, the hit is extended out ±0.1cM. These hits are then merged together to form regions of the genome that are of interest to this disease.

The alleles shown are major allele > minor allele, with the odds ratio being defined for the risk allele. Other signals located in the same region as the primary signal have a pale yellow background and are shown in italics

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UC 1p36.23

chr1:7853370-8140630

rs35675666

TNFRSF9 ERRFI1 PARK7 UTS2

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1p36.23	chr1:7853370-8140630	rs35675666 G>T	5.95e-13^C	1.14 (1.08-1.19)^C	G	024
1p36.23	chr1:7853370-8140630	rs35675666 G>T	4.84e-09^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs35675666 G>T	UC	029	4.84e-09^C
rs35675666 G>T	UC	024	5.95e-13^C	1.14 (1.08-1.19)^C	G
rs35675666 G>T	IBD	017	1.12e-15^C	1.11 (1.06-1.15)^C	G
rs35675666 G>T	CRO	021	1.13e-07^C	1.1 (1.05-1.15)^C	G

Genes

Protein-coding Genes UTS2 PARK7 TNFRSF9 ERRFI1
Non-coding Genes CTA-215D11.4 Y_RNA RP5-892F13.2 RP11-431K24.1
Protein Coding Genes +/-0.5Mb of Region PER3 CAMTA1 VAMP3 SLC45A1 RERE
Non-coding Genes +/-0.5Mb of Region CAMTA1-IT1 RP3-467L1.6 RP3-467L1.4 RP4-549F15.1 RP11-338N10.2 RP3-453P22.2 RP11-338N10.1 RP11-338N10.3 RP11-431K24.3 RNU1-7P RNU6-991P RP5-1115A15.2 RP11-431K24.4 Y_RNA RP5-1115A15.1 AL096855.1 SNORA77 RP11-431K24.2

UC 1p36.13

chr1:19821756-19953230

rs6426833

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1p36.13	chr1:19821756-19953230	rs6426833 A>G	2.39e-68^C	1.27 (1.22-1.32)^C	A	024
1p36.13	chr1:19821756-19953230	rs6426833 A>G	3.93e-35^D	1.3 (1.25-1.35)^D	A	029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs6426833	IBD	017	1.06e-13	1.11	A
rs6426833	UC		3.77e-76	1.26	A
rs6426833 A>G	UC	029	3.93e-35^D	1.3 (1.25-1.35)^D	A
rs6426833 A>G	UC	024	2.39e-68^C	1.27 (1.22-1.32)^C	A

Genes

Protein-coding Genes PLA2G2E OTUD3
Non-coding Genes
Protein Coding Genes +/-0.5Mb of Region RNF186 TMCO4 PQLC2 HTR6 MINOS1-NBL1 NBL1 CAPZB MINOS1 UBXN10 PLA2G2A PLA2G2D PLA2G2F PLA2G5 VWA5B1 PLA2G2C
Non-coding Genes +/-0.5Mb of Region RP11-91K11.2 RNU4-28P RN7SL277P RP5-1056L3.3 RP5-1056L3.1 RN7SL304P RP3-340N1.2 RP3-340N1.6 LINC01141 RP4-745E8.2 RP4-749H3.2 UBXN10-AS1

UC 1p36.33

chr1:1190173-1452909

rs12103

TNFRSF18 TNFRSF4

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1p36.33	chr1:1190173-1452909	rs12103 G>A	2.73e-10^C	1.11 (1.06-1.16)^C	A	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs12103 G>A	IBD	017	7.66e-13^C	1.10 (1.06-1.14)^C	A
rs12103 G>A	UC	024	2.73e-10^C	1.11 (1.06-1.16)^C	A
rs12103 G>A	CRO	021	6.96e-08^C	1.09 (1.04-1.13)^C	A

Genes

Protein-coding Genes MXRA8 CPSF3L TMEM88B UBE2J2 FAM132A ACAP3 CCNL2 B3GALT6 SDF4 ANKRD65 TNFRSF18 DVL1 SCNN1D PUSL1 TTLL10 TNFRSF4 MRPL20 VWA1 CPTP AURKAIP1 TAS1R3 ATAD3C
Non-coding Genes RP5-902P8.10 MIR6726 RP4-758J18.10 RP4-758J18.2 MIR6808 RP5-902P8.12 MIR6727 RP5-890O3.9 RP4-758J18.13 RP4-758J18.7 NDUFB4P8 RN7SL657P
Protein Coding Genes +/-0.5Mb of Region RNF223 PLEKHN1 NOC2L C1orf159 KLHL17 ISG15 PERM1 HES4 SAMD11 AGRN CFAP74 ATAD3A MIB2 TMEM240 AL645728.1 SLC35E2 NADK ATAD3B C1orf233 SSU72 TMEM52 GNB1 CALML6 CDK11A CDK11B SLC35E2B MMP23B
Non-coding Genes +/-0.5Mb of Region RP11-206L10.4 FAM166AP3 RP11-54O7.16 RP11-54O7.18 RP11-465B22.8 TTLL10-AS1 LINC01342 MIR429 RP11-206L10.2 RP11-206L10.9 RP11-54O7.1 RP11-54O7.10 RP11-54O7.11 RP11-54O7.3 FAM87B TUBB8P11 RP11-54O7.2 AL645608.1 MIR200B MIR200A CICP3 RNU6-1199P RP11-206L10.8 RP11-465B22.3 LINC01128 FAM41C LINC00115 RP11-54O7.17 RP11-54O7.14 RP5-857K21.4 RP5-832C2.5 RP11-345P4.7 MMP23A Metazoa_SRP RP1-283E3.4 RP11-345P4.11 RP11-345P4.9 RP1-283E3.8 RP1-140A9.1 RP11-345P4.10 RP11-345P4.6

UC 1p36.32

chr1:2431888-2879054

rs734999 rs10797432

PLCH2 FAM213B MMEL1 TNFRSF14

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1p36.32	chr1:2431888-2879054	rs10797432 C>T	2.62e-12^C	1.08 (1.04-1.11)^C	C	024
1p36.32	chr1:2431888-2879054	rs734999 C>T	3.34e-09^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs734999	UC		2.70e-09	1.08	G
rs734999 C>T	UC	029	3.34e-09^C
rs10797432 C>T	IBD	017	4.65e-07^C	1.03 (1.01-1.06)^C	C
rs10797432 C>T	UC	024	2.62e-12^C	1.08 (1.04-1.11)^C	C

Genes

Protein-coding Genes PLCH2 FAM213B PANK4 TNFRSF14 MMEL1 TTC34 HES5
Non-coding Genes RP3-395M20.12 RP3-395M20.8 RP11-740P5.2 RP3-395M20.3 RP13-436F16.1 RP3-395M20.9 RP11-740P5.3 RP3-395M20.7 RP3-395M20.2
Protein Coding Genes +/-0.5Mb of Region FAAP20 MORN1 CFAP74 PRKCZ PEX10 RER1 GABRD SKI PRDM16 ACTRT2
Non-coding Genes +/-0.5Mb of Region RP5-892K4.1 RP11-547D24.3 RP11-181G12.2 RP11-181G12.4 AL590822.1 RP4-713A8.1 RP4-740C4.7 RP11-547D24.1 RP4-740C4.5 RP11-22L13.1 LINC00982 RP11-193J6.1 RP1-163G9.2

UC 1q23.3

chr1:161419627-161668253

rs1801274

FCRLA FCGR3B FCGR2A FCGR2B FCGR3A HSPA6

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1q23.3	chr1:161419627-161668253	rs1801274 A>G	2.12e-38^C	1.19 (1.15-1.23)^C	A	024
1q23.3	chr1:161419627-161668253	rs1801274 A>G	2.16e-20^D	1.2 (1.16-1.27)^D	A	029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs1801274	UC		1.43e-41	1.19	A
rs1801274 C>T	AS	026	1.40e-09^C	1.11^C	T
rs1801274 A>G	SLE	015	4.10e-04^C	1.16 (1.09-1.20)^C	G
rs1801274 A>G	UC	029	2.16e-20^D	1.2 (1.16-1.27)^D	A
rs1801274 A>G	CRO	021	1.53e-07^C	1.08 (1.04-1.11)^C	A
rs1801274 A>G	SLE	047	1.04e-12^C	1.21 (1.11-1.21)^D	G
rs1801274 A>G	IBD	017	3.52e-28^C	1.12 (1.09-1.16)^C	A
rs1801274 A>G	UC	024	2.12e-38^C	1.19 (1.15-1.23)^C	A

Genes

Protein-coding Genes HSPA6 FCGR2B FCGR3B FCGR2A FCGR3A
Non-coding Genes RPS23P9 RP11-25K21.6 RPS23P10 FCGR2C HSPA7 RP11-5K23.5
Protein Coding Genes +/-0.5Mb of Region USP21 DEDD MPZ AL591806.1 UFC1 TSTD1 KLHDC9 NDUFS2 NR1I3 F11R USF1 RP11-544M22.13 SDHC TOMM40L FCER1G B4GALT3 CFAP126 ARHGAP30 NIT1 PVRL4 ADAMTS4 APOA2 PCP4L1 ITLN2 PFDN2 PPOX OLFML2B NOS1AP DUSP12 FCRLB FCRLA ATF6
Non-coding Genes +/-0.5Mb of Region RRM2P2 RP11-544M22.1 RP11-297K8.2 RNU6-481P RP11-122G18.7 ACA64 RP11-312J18.6 RP11-544M22.8 MIR5187 RP11-312J18.7 RP11-544M22.3 RP11-122G18.9 RP11-227F8.2 RP11-25K21.1 Y_RNA RP11-474I16.8 MIR4654 RPL31P11 RN7SL466P RP11-456P18.2

UC 1p31.3

chr1:67128876-67302310

rs11209026

IL12RB2 IL23R

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1p31.3	chr1:67128876-67302310	rs11209026 G>A	3.20e-62^C	1.69 (1.56-1.82)^C	G	024
1p31.3	chr1:67128876-67302310	rs11209026 G>A	5.12e-28^D	1.75 (1.56-1.92)^D	G	029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs11209026	AS	026	1.94e-27	1.11	G
rs11209026	IBD	017	1.01e-96	2.01	G
rs11209026 G>A	PSO	013	7.13e-07^D	1.49 (1.75-1.27)^D	G
rs11209026 G>A	UC	029	5.12e-28^D	1.75 (1.56-1.92)^D	G
rs11209026 G>A	CRO	021	1.02e-146^C	2.38 (2.17-2.56)^C	G
rs11209026 G>A	AS	012	9.10e-14^C	1.89 (1.56-2.27)^D	G
rs11209026 G>A	UC	024	3.20e-62^C	1.69 (1.56-1.82)^C	G
rs11209026 G>A	CRO	011	1.00e-64^D	2.63 (2.38-3.03)^D	G

Genes

Protein-coding Genes IL23R C1orf141
Non-coding Genes AL109843.1 RNU6-586P RNU4ATAC4P RP11-131O15.2
Protein Coding Genes +/-0.5Mb of Region MIER1 INSL5 WDR78 SLC35D1 TCTEX1D1 SGIP1 GNG12 IL12RB2 SERBP1 GADD45A
Non-coding Genes +/-0.5Mb of Region RP4-598P13.1 RP4-547N15.3 SNORA31 AL354978.1 RP11-342H21.2 RNU6-1031P RP11-393N21.2 RN7SL392P RNU6-387P RP11-393N21.1 HNRNPCP9 RNU7-80P

UC 1q32.1

chr1:200062588-200168521

rs2816958

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1q32.1	chr1:200062588-200168521	rs2816958 G>A	1.98e-17^C	1.23 (1.16-1.3)^C	G	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs2816958	UC		1.14e-18	1.20	G
rs2816958 G>A	UC	024	1.98e-17^C	1.23 (1.16-1.3)^C	G
rs2816958 G>A	IBD	017	8.22e-10^C	1.12 (1.08-1.18)^C	G

Genes

Protein-coding Genes NR5A2
Non-coding Genes RP11-47A17.2 AC096633.1
Protein Coding Genes +/-0.5Mb of Region KIF14 DDX59 ZNF281
Non-coding Genes +/-0.5Mb of Region RNU6-778P RNU6-609P RP11-567B20.1 RP11-567B20.2 RNU6-716P AL450244.1 RP11-2L13.1 RNU6-570P RP11-532L16.3 LINC00862 AL590126.1 FAM58BP RP11-532L16.1 RP11-469A15.2 RP11-121P12.1

UC 1p36.12

chr1:22326008-22411939

rs12568930 rs7524102

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1p36.12	chr1:22326008-22411939	rs12568930 T>C	1.26e-17^C	1.15 (1.1-1.2)^C	T	024
1p36.12	chr1:22326008-22411939	rs7524102 A>G	1.65e-13^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs7524102	UC	024	2.45e-08	1.14	A
rs12568930	UC		4.40e-13	1.14	A
rs12568930 T>C	IBD	017	7.42e-14^C	1.1 (1.05-1.14)^C	T
rs7524102 A>G	UC	029	1.65e-13^C

Genes

Protein-coding Genes
Non-coding Genes RP11-415K20.2
Protein Coding Genes +/-0.5Mb of Region CELA3B WNT4 CDC42 HSPG2 CELA3A C1QA C1QC EPHA8 ZBTB40 EPHB2 C1QB
Non-coding Genes +/-0.5Mb of Region CDC42-IT1 RP1-224A6.3 RNU6-776P RP1-224A6.8 RP11-415K20.1 RNU6-1022P RP11-26H16.1 RN7SL386P RP1-224A6.9 MIR4418 LINC00339 RN7SL186P AL158086.1 MIR4684 ZBTB40-IT1 AL611946.1 RP11-69E9.1 MIR4253

UC 1q32.1

chr1:200892467-201069559

rs7554511

C1orf106 KIF21B

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1q32.1	chr1:200892467-201069559	rs7554511 C>A	9.74e-25^C	1.18 (1.14-1.22)^C	C	024
1q32.1	chr1:200892467-201069559	rs7554511 C>A	2.04e-13^D			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs7554511	CRO		2.09e-27	1.16	C
rs7554511	IBD	017	1.04e-20	1.16	C
rs7554511 C>A	UC	024	9.74e-25^C	1.18 (1.14-1.22)^C	C
rs7554511 C>A	UC	029	2.04e-13^D
rs7554511 C>A	CRO	011	1.58e-07^D	1.14 (1.08-1.19)^D	C
rs7554511 C>A	CRO	021	7.81e-19^C	1.15 (1.11-1.19)^C	C

Genes

Protein-coding Genes C1orf106 KIF21B CACNA1S
Non-coding Genes MROH3P RNU6-704P RP11-168O16.1 RP11-168O16.2
Protein Coding Genes +/-0.5Mb of Region CAMSAP2 KIF14 DDX59 ZNF281 GPR25 IGFN1 TNNT2 LAD1 PKP1 TNNI1 ASCL5 PHLDA3 CSRP1 TMEM9
Non-coding Genes +/-0.5Mb of Region RPL34P6 RP11-92G12.3 RP11-469A15.2 RP11-121P12.1 RP11-134G8.2 RP11-567E21.3 RP11-27G14.4 RP11-134G8.10 RP11-134G8.5 RP11-134G8.7 RP11-134G8.6

UC 1q21.3

chr1:151565936-152018664

rs4845604

RORC

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1q21.3	chr1:151565936-152018664	rs4845604 G>A	3.52e-16^C	1.19 (1.14-1.25)^C	G	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs4845604	UC	024	1.58e-11	1.19	G
rs4845604	IBD	017	9.41e-11	1.14	G
rs4845604 G>A	CRO	021	1.88e-06^C	1.11 (1.05-1.16)^C	G

Genes

Protein-coding Genes S100A10 C2CD4D RORC RIIAD1 LINGO4 OAZ3 THEM5 THEM4 TDRKH TUFT1 CELF3 SNX27 MRPL9
Non-coding Genes KRT8P28 AL450992.2 RP11-98D18.1 RP11-98D18.17 RP11-98D18.2 RP11-98D18.15 AL450992.6 RP11-404E16.1 Y_RNA RNU6-662P RP11-98D18.7 RNU6-1062P RP11-98D18.3 RP11-98D18.16 AL591893.1 RP11-98D18.9
Protein Coding Genes +/-0.5Mb of Region PSMD4 TNFAIP8L2 PI4KB GABPB2 TMOD4 LYSMD1 ZNF687 VPS72 RFX5 MLLT11 PSMB4 CDC42SE1 SCNM1 SELENBP1 CGN SEMA6C PIP5K1A POGZ AL135842.1 S100A11 FLG CRCT1 RPTN HRNR LCE5A TCHHL1 CRNN FLG2 TCHH LCE3C
Non-coding Genes +/-0.5Mb of Region RP11-126K1.8 RP11-68I18.2 RP11-126K1.9 SNORA44 RP11-68I18.10 RP11-74C1.2 RP11-126K1.2 RNY4P25 MIR554 RN7SL444P RP11-126K1.6 RP11-74C1.4 AL589986.2 PUDPP2 RP11-107M16.2 SPTLC1P4 HMGN3P1 FLG-AS1

UC 1q23.3

chr1:160727284-160979324

rs4656958

F11R ITLN1 USF1 CD48 SLAMF7 CD244 SLAMF1 ARHGAP30

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1q23.3	chr1:160727284-160979324	rs4656958 G>A	6.95e-08^C	1.08 (1.03-1.11)^C	G	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs4656958 G>A	IBD	017	6.80e-09^C	1.06 (1.03-1.1)^C	G
rs4656958 G>A	UC	024	6.95e-08^C	1.08 (1.03-1.11)^C	G

Genes

Protein-coding Genes CD244 ITLN1 LY9 SLAMF7 ITLN2
Non-coding Genes RP11-404F10.5 RP11-544M22.1 RP11-312J18.5 RP11-312J18.6 RP11-312J18.3 RP11-312J18.7 RP11-404F10.6
Protein Coding Genes +/-0.5Mb of Region NCSTN COPA SLAMF1 SLAMF6 CD48 CD84 NHLH1 RP11-574F21.3 VANGL2 DCAF8 PEX19 USP21 DEDD MPZ AL591806.1 UFC1 TSTD1 KLHDC9 NDUFS2 NR1I3 F11R USF1 RP11-544M22.13 SDHC TOMM40L FCER1G B4GALT3 CFAP126 ARHGAP30 NIT1 PVRL4 ADAMTS4 APOA2 PCP4L1 PFDN2 PPOX
Non-coding Genes +/-0.5Mb of Region RP11-574F21.2 RPSAP18 SETP9 SUMO1P3 Y_RNA RNU4-42P RP11-528G1.2 RP11-404F10.2 RRM2P2 RP11-297K8.2 RNU6-481P RP11-122G18.7 ACA64 RP11-544M22.8 MIR5187 RP11-544M22.3 RP11-122G18.9

UC 1q31.3

chr1:197342098-197969200

rs2488389

C1orf53

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1q31.3	chr1:197342098-197969200	rs2488389 G>A	6.79e-06^C	1.11 (1.06-1.15)^C	A	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs2488389	IBD	017	6.14e-10	1.11	A
rs2488389 G>A	UC	024	6.79e-06^C	1.11 (1.06-1.15)^C	A
rs2488389 G>A	CRO	021	8.45e-13^C	1.12 (1.08-1.17)^C	A

Genes

Protein-coding Genes C1orf53 DENND1B LHX9 CRB1
Non-coding Genes MRPS21P3 RP11-448G4.2 RP11-448G4.4 Y_RNA EEF1A1P32 RP11-75C23.1 FAM204BP
Protein Coding Genes +/-0.5Mb of Region F13B ZBTB41 CFHR2 CFHR4 CFHR5 RP4-608O15.3 ASPM NEK7
Non-coding Genes +/-0.5Mb of Region SEPT14P12 RP4-608O15.4 RP11-332L8.1 PRR13P1 AC093419.1

UC 1q32.1

chr1:206709013-206867232

rs3024505

IL20 PIGR FCMR IL24 IL19 RASSF5 MAPKAPK2 IL10

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1q32.1	chr1:206709013-206867232	rs3024505 G>A	6.94e-41^C	1.28 (1.22-1.34)^C	A	024
1q32.1	chr1:206709013-206867232	rs3024505 G>A	5.76e-17^D	1.25 (1.19-1.32)^D	A	029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs3024505	IBD	017	1.20e-22	1.21	A
rs3024505	UC		4.71e-43	1.25	A
rs3024505	CRO	021	8.14e-12	1.16	A
rs3024505 G>A	UC	029	5.76e-17^D	1.25 (1.19-1.32)^D	A
rs3024505 G>A	T1D	025	6.40e-08^D	1.16^D	G
rs3024505 C>T	T1D	004	1.90e-09^C	1.19 (1.1-1.3)^C	C
rs3024505 G>A	SLE	015	4.00e-08^C	1.19 (1.11-1.28)^C	A
rs3024505 G>A	SLE	047	4.64e-09^C	1.12 (1.11-1.24)^D	A
rs3024505 C>T	CRO	011	1.60e-14^C	1.12 (1.07-1.17)^C	T
rs3024505 G>A	UC	024	6.94e-41^C	1.28 (1.22-1.34)^C	A

Genes

Protein-coding Genes IL20 IL19 IL10 MAPKAPK2
Non-coding Genes Y_RNA
Protein Coding Genes +/-0.5Mb of Region SRGAP2 IKBKE RASSF5 DYRK3 EIF2D C4BPB C1orf116 CD55 YOD1 FCAMR PIGR IL24 PFKFB2 C4BPA FCMR
Non-coding Genes +/-0.5Mb of Region C1orf147 CH17-76K2.6 RP11-421E17.4 RP11-534L20.5 RP11-343H5.6 RP11-534L20.4 RP11-343H5.4 MIR6769B RP11-564A8.4 RP11-164O23.8 RP11-564A8.8 RP11-164O23.7 RP11-164O23.5 C4BPAP2 RP11-6J21.2 C4BPAP1

UC 1p31.1

chr1:70524556-70651887

rs2651244

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
1p31.1	chr1:70524556-70651887	rs2651244 G>A	2.29e-08^C	1.08 (1.03-1.11)^C	G	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs2651244 G>A	UC	024	2.29e-08^C	1.08 (1.03-1.11)^C	G

Genes

Protein-coding Genes
Non-coding Genes RP11-42O15.2
Protein Coding Genes +/-0.5Mb of Region AL158839.1 HHLA3 LRRC40 ANKRD13C LRRC7 SRSF11 CTH PTGER3 ZRANB2
Non-coding Genes +/-0.5Mb of Region RP11-180O5.2 Metazoa_SRP RP11-181B18.1 RP4-677H15.4 RN7SL242P RP11-42O15.3 RP3-333A15.1 ZRANB2-AS2 CASP3P1 RP11-99H8.1 ZRANB2-AS1 AL360297.1 RP5-952N6.1 MIR186 RP3-333A15.2

UC 2q37.3

chr2:240619922-240716127

rs3749171 rs4676406

GPR35

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
2q37.3	chr2:240621671-240716127	rs4676406 T>G	8.32e-11^D	1.14 (1.09-1.18)^D	T	029
2q37.3	chr2:240619922-240712978	rs3749171 C>T	3.07e-21^C	1.17 (1.12-1.22)^C	T	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs3749171	UC	024	1.48e-11	1.17	A
rs3749171	IBD	017	2.00e-11	1.14	A
rs3749171	AS	026	1.19e-08	1.03	T
rs4676406 T>G	UC	029	8.32e-11^D	1.14 (1.09-1.18)^D	T
rs3749171 C>T	CRO	021	3.02e-08^C	1.11 (1.06-1.15)^C	T

Genes

Protein-coding Genes AQP12B GPR35 KIF1A AQP12A
Non-coding Genes RP11-118M12.2 AC011298.2 RP11-118M12.1
Protein Coding Genes +/-0.5Mb of Region OTOS DUSP28 GPC1 RNPEPL1 ANKMY1 CAPN10 MYEOV2 MTERF4 AGXT CROCC2 PASK SNED1 ANO7 C2orf54 PPP1R7
Non-coding Genes +/-0.5Mb of Region AC124861.2 PP14571 AC124861.1 U3 CAPN10-AS1 MIR149 AC005237.4 AC104809.4 AC104809.2 AC005237.2 AC093585.6

UC 2p23.3

chr2:24464482-25234839

rs6545800

ADCY3

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
2p23.3	chr2:24464482-25234839	rs6545800 C>T	4.05e-06^C	1.07 (1.03-1.11)^C	T	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs6545800 C>T	UC	024	4.05e-06^C	1.07 (1.03-1.11)^C	T
rs6545800 C>T	IBD	017	9.40e-15^C	1.11 (1.08-1.14)^C	T
rs6545800 C>T	CRO	021	6.14e-16^C	1.14 (1.10-1.18)^C	T

Genes

Protein-coding Genes CENPO PTRHD1 NCOA1 DNMT3A DNAJC27 ADCY3 EFR3B POMC
Non-coding Genes RN7SL856P RNU6-936P AC013267.1 Y_RNA LINC01381 DNAJC27-AS1 SUCLA2P3 RNA5SP88 SNORD14 RP11-443B20.1
Protein Coding Genes +/-0.5Mb of Region SF3B6 ITSN2 FAM228B C2orf44 UBXN2A RP11-507M3.1 TP53I3 MFSD2B FAM228A FKBP1B PFN4 DTNB ASXL2
Non-coding Genes +/-0.5Mb of Region RNU6-370P HMGN2P20 AC008073.9 AC066692.1 AC009228.1 RPL36AP13 AC008073.7 SCARNA21 RN7SL610P Y_RNA AC012074.2 MIR1301 AC104699.1 AC010150.2

UC 2p16.1

chr2:60706158-61642429

rs7608910

AHSA2 C2orf74 REL PUS10 KIAA1841

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
2p16.1	chr2:60706158-61642429	rs7608910 A>G	1.70e-14^D	1.19 (1.14-1.24)^D	G	029
2p16.1	chr2:60706158-61642429	rs7608910 A>G	6.57e-25^C	1.15 (1.11-1.19)^C	G	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs7608910	UC		1.25e-23	1.14	G
rs7608910	CRO		2.95e-23	1.13	G
rs7608910	IBD	017	1.49e-18	1.14	G
rs7608910 A>G	UC	024	6.57e-25^C	1.15 (1.11-1.19)^C	G
rs7608910 A>G	CRO	021	6.92e-19^C	1.13 (1.09-1.17)^C	G
rs7608910 A>G	UC	029	1.70e-14^D	1.19 (1.14-1.24)^D	G

Genes

Protein-coding Genes C2orf74 PUS10 PAPOLG KIAA1841 USP34 XPO1 REL AHSA2 PEX13
Non-coding Genes RNU6-612P AC016727.3 LINC01185 AC010733.5 AC016747.1 RP11-355B11.2 RNU6-1145P RP11-373L24.1 RP11-479F13.1 RP11-493E12.2 RP11-416L21.1 RN7SL632P RPL21P33 ATP1B3P1 AC016727.1 RNU4-51P RP11-493E12.3 RP11-493E12.1 AC016747.3 NONOP2 RNA5SP95 RP11-355B11.1 SNORA70B AC016894.1
Protein Coding Genes +/-0.5Mb of Region BCL11A AC107081.1 CCT4 FAM161A COMMD1
Non-coding Genes +/-0.5Mb of Region MIR4432 MIR4432HG RN7SL361P RP11-416L21.2 AC007381.3 RNU1-32P AC007381.1 AC009970.1 AC108039.3 RP11-681L4.1 RP11-681L4.2 AC108039.1 RPS24P7 AC018462.2 AC107081.5 Y_RNA

UC 2q11.2

chr2:101678428-102080305

rs2310173

IL1R2

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
2q11.2	chr2:101678428-102080305	rs2310173 G>T	3.17e-12^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs2310173	CRO		7.46e-09	1.07	A
rs2310173 C>A	AS	012	4.80e-07^C	1.18 (1.10-1.27)^D	A
rs2310173 G>T	UC	029	3.17e-12^C

Genes

Protein-coding Genes MAP4K4 IL1R2 IL1R1
Non-coding Genes LINC01127
Protein Coding Genes +/-0.5Mb of Region CREG2 TBC1D8 RFX8 CNOT11 RNF149 SLC9A4 IL1RL1 IL18RAP IL18R1 IL1RL2
Non-coding Genes +/-0.5Mb of Region SNORD89 AC092570.4 AC013722.1 AC092570.1 MIR5696 AC092570.2 AC092570.3 FAM183DP SDR42E1P5 AC007278.3 MIR4772 AC007271.3 AC007278.2

UC 2q33.1

chr2:197277486-198096744

rs1016883

RFTN2 PLCL1

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
2q33.1	chr2:197277486-198096744	rs1016883 C>A	2.87e-08^C	1.1 (1.05-1.15)^C	C	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs1016883 C>A	UC	024	2.87e-08^C	1.1 (1.05-1.15)^C	C

Genes

Protein-coding Genes RFTN2 HSPD1 ANKRD44 SF3B1 MOB4 HSPE1-MOB4 PLCL1 BOLL COQ10B HSPE1 MARS2
Non-coding Genes SNORA4 RNU6-1029P AC020550.7 AC010746.3 AC011997.1 NPM1P46 ANKRD44-IT1
Protein Coding Genes +/-0.5Mb of Region GTF3C3 PGAP1 C2orf66
Non-coding Genes +/-0.5Mb of Region RP11-84A12.1 HNRNPA3P15 AC017035.2 AC013264.2 ATP5G2P3 AC109589.1 AC019330.1 AC005235.1 AC019330.2

UC 2q32.3

chr2:190986040-191143008

rs1517352

STAT1 STAT4

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
2q32.3	chr2:190986040-191143008	rs1517352 C>A	1.55e-06^C	1.05 (1.02-1.1)^C	C	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs1517352	CRO		1.31e-10	1.08	C
rs1517352	UC		2.10e-09	1.08	C
rs1517352 C>A	IBD	017	3.28e-11^C	1.08 (1.04-1.11)^C	C
rs1517352 C>A	CRO	021	1.93e-10^C	1.1 (1.05-1.14)^C	C
rs1517352 C>A	UC	024	1.55e-06^C	1.05 (1.02-1.1)^C	C

Genes

Protein-coding Genes STAT4 STAT1
Non-coding Genes AC067945.2 RNU6-959P AC067945.3 AC067945.4
Protein Coding Genes +/-0.5Mb of Region NEMP2 MFSD6 GLS NAB1 MYO1B
Non-coding Genes +/-0.5Mb of Region AC093388.3 AC006460.2 RN7SKP179 AC005540.1 AC005540.3 HMGB1P27 AC092614.2 AC068056.1 RP11-317J9.1 AC092614.1 RNU6-1045P

UC 2q35

chr2:218018463-218395928

rs11676348 rs2382817

CXCR1 PNKD AAMP CXCR2 TMBIM1 SLC11A1 CTDSP1 ARPC2

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
2q35	chr2:218074907-218395928	rs2382817 C>A	5.38e-08^C	1.05 (1.02-1.09)^C	A	024
2q35	chr2:218018463-218377795	rs11676348 C>T	1.25e-10^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs11676348	UC		2.08e-09	1.08	A
rs11676348	CRO		3.65e-09	1.07	A
rs2382817	UC		1.54e-08	1.07	A
rs2382817 C>A	CRO	021	1.28e-07^C	1.09 (1.05-1.12)^C	A
rs11676348 C>T	UC	029	1.25e-10^C
rs2382817 C>A	UC	024	5.38e-08^C	1.05 (1.02-1.09)^C	A
rs2382817 C>A	IBD	017	3.70e-12^C	1.07 (1.04-1.10)^C	A

Genes

Protein-coding Genes RUFY4 ARPC2 SLC11A1 CXCR1 PNKD CXCR2 TMBIM1 GPBAR1 AAMP CATIP
Non-coding Genes CATIP-AS2 CATIP-AS1 CXCR2P1 AC021016.7 MIR6513 HMGB1P9 AC097483.1 RP11-378A13.1 MIR6810
Protein Coding Genes +/-0.5Mb of Region DIRC3 TNS1 WNT6 BCS1L RQCD1 PRKAG3 WNT10A USP37 ZNF142 STK36 CYP27A1 TTLL4 VIL1 PLCD4 RNF25 CTDSP1
Non-coding Genes +/-0.5Mb of Region AC010886.2 RPL7L1P9 MIR6809 AC010136.2 RP11-548H3.1 RP11-459I19.1 RN7SKP38 RPL23AP31 RP11-378A13.2 RNU6-136P MIR26B

UC 2q33.1

chr2:198492027-198792296

rs17229285

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
2q33.1	chr2:198492027-198792296	rs17229285 T>C	1.73e-13^C	1.12 (1.08-1.16)^C	C	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs17229285	UC	024	3.59e-10	1.12	G
rs17229285 T>C	IBD	017	3.76e-06^C	1.06 (1.03-1.09)^C	C

Genes

Protein-coding Genes PLCL1
Non-coding Genes AC019330.1 AC068121.1 AC019330.2
Protein Coding Genes +/-0.5Mb of Region SATB2
Non-coding Genes +/-0.5Mb of Region AC109589.1 AC005235.1 RNU7-147P AC018717.1 AC018717.2

UC 2q24.2

chr2:162104363-162502867

rs2111485

IFIH1

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
2q24.2	chr2:162104363-162502867	rs2111485 G>A	1.93e-08^C	1.09 (1.05-1.12)^C	A	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs2111485	T1D	025	3.81e-18	1.18	G
rs2111485	UC		2.11e-10	1.09	A
rs2111485 G>A	VIT	036	4.91e-15^C	1.3^D	G
rs2111485 G>A	UC	024	1.93e-08^C	1.09 (1.05-1.12)^C	A
rs2111485 G>A	SLE	047	1.27e-11^C	1.15 (1.2-1.11)^D	G
rs2111485 G>A	IBD	017	2.52e-07^C	1.07 (1.04-1.10)^C	A

Genes

Protein-coding Genes IFIH1 GCA GCG FAP KCNH7
Non-coding Genes RNA5SP109 AC007750.1 AC007750.5
Protein Coding Genes +/-0.5Mb of Region DPP4 SLC4A10
Non-coding Genes +/-0.5Mb of Region TIMM8AP1 AC008063.2 AC008063.3 AC092841.1 RPEP5 AC092841.2 EIF3EP2 AC007740.1

UC 3p21.1

chr3:52314348-53145738

rs9847710

PRKCD ITIH4

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
3p21.1	chr3:52314348-53145738	rs9847710 T>C	1.05e-08^C	1.06 (1.03-1.10)^C	C	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs9847710 T>C	UC	024	1.05e-08^C	1.06 (1.03-1.10)^C	C

Genes

Protein-coding Genes TNNC1 PBRM1 RFT1 ITIH3 ITIH4 ITIH1 GLT8D1 NEK4 SMIM4 DNAH1 SEMA3G RP11-894J14.5 NISCH RP5-966M1.6 SPCS1 TMEM110 TMEM110-MUSTN1 STAB1 GNL3 PHF7 MUSTN1 NT5DC2 BAP1 SFMBT1
Non-coding Genes SNORD19B RP5-966M1.5 RNU6ATAC16P RP5-966M1.4 ITIH4-AS1 RP11-168J18.6 RP5-966M1.7 RP11-894J14.2 SNORD19 RNU6-856P SNORD19 SNORD69 SNORD19B SNORD19 RP11-5O17.1 SERBP1P3 MIR8064
Protein Coding Genes +/-0.5Mb of Region IQCF2 PCBP4 IQCF3 TLR9 ABHD14A WDR82 GLYCTK ACY1 RP11-330H6.5 RRP9 TWF2 ABHD14B RPL29 ABHD14A-ACY1 POC1A PPM1M ALAS1 IQCF1 DUSP7 PARP3 GPR62 IQCF5 PRKCD CACNA1D TKT DCP1A
Non-coding Genes +/-0.5Mb of Region IQCF4 MIR135A1 RN7SL504P RP11-155D18.13 IQCF5-AS1 RP11-330H6.6 GLYCTK-AS1 ALDOAP1 RP11-155D18.12 RP5-1157M23.2 MIRLET7G SNORD63 RP11-72H11.1 Y_RNA SNORA26 SNORD38

UC 3p21.31

chr3:48456895-50711580

rs9822268 rs3197999

IP6K2 UCN2 APEH AMIGO3 MST1R UBA7 GMPPB GPX1 PFKFB4 IP6K1 USP4 MST1 BSN

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
3p21.31	chr3:48456895-50711580	rs9822268 G>A	1.60e-17^D	1.21 (1.16-1.26)^D	A	029
3p21.31	chr3:48465783-50711580	rs3197999 G>A	5.60e-36^C	1.21 (1.16-1.25)^C	A	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs3197999	UC	024	1.30e-22	1.21	A
rs9822268	CRO		8.98e-33	1.16	A
rs3197999	UC		2.24e-37	1.19	A
rs9822268	IBD	017	8.18e-25	1.17	A
rs9822268 G>A	UC	029	1.60e-17^D	1.21 (1.16-1.26)^D	A
rs3197999 G>A	PSC	032	2.45e-26^D	1.33 (1.26-1.40)^D	A
rs3197999 G>A	CRO	011	6.17e-17^D	1.22 (1.16-1.27)^D	A
rs3197999 G>A	CRO	021	5.31e-29^C	1.16 (1.12-1.20)^C	A

Genes

Protein-coding Genes UCN2 IMPDH2 GNAI2 AMIGO3 TUSC2 CCDC36 COL7A1 SLC38A3 CISH IP6K2 NCKIPSD PFKFB4 MON1A MST1 HYAL2 RBM5 CDHR4 IP6K1 SHISA5 HYAL1 ATRIP DAG1 RHOA RNF123 IFRD2 GNAT1 MST1R LSMEM2 CELSR3 NPRL2 DOCK3 USP4 KLHDC8B P4HTM AMT HYAL3 C3orf62 ATRIP BSN PRKAR2A NICN1 C3orf84 HEMK1 ZMYND10 RBM6 QRICH1 USP19 TREX1 ARIH2 WDR6 XXcos-LUCA11.5 TMEM89 GMPPB RASSF1 C3orf18 FAM212A CYB561D2 CAMKV UBA7 ARIH2OS SLC26A6 QARS UQCRC1 SEMA3F TMEM115 CCDC71 LAMB2 APEH SEMA3B MAPKAPK3 DALRD3 GPX1 NAT6 NDUFAF3 SLC25A20 TCTA CACNA2D2 TRAIP
Non-coding Genes RP11-3B7.7 MIR6823 MIR4793 CYB561D2 MIR4787 MIR425 RHOA-IT1 CTD-2330K9.2 ZMYND10-AS1 COX6CP14 AC134772.1 AC141002.1 Metazoa_SRP AC099668.5 AC139451.2 RP11-804H8.6 PRKAR2A-AS1 MIR6872 MIR5193 MIR711 RP13-131K19.1 RP13-131K19.2 MIR6890 MIR5787 RP11-3B7.1 RP11-804H8.7 MIR566 BSN-AS2 RP13-131K19.7 AC099668.1 AC139451.1 RN7SL217P ACTBP13 SEMA3B-AS1 RP13-131K19.6 RP11-694I15.7 XXcos-LUCA16.1 RN7SL182P RASSF1-AS1 RNA5SP130 RP11-572O6.1 RP13-1056D16.2 BSN-AS1 CTD-2330K9.3 SEMA3F-AS1 U73166.2 RNA5SP131 RP11-804H8.5 CELSR3-AS1 MIR6824 MIR4271 Y_RNA RBM5-AS1 MIR191
Protein Coding Genes +/-0.5Mb of Region MAP4 CDC25A PLXNB1 ZNF589 SPINK8 CAMP TMA7 NME6 FBXW12 CCDC51
Non-coding Genes +/-0.5Mb of Region AC124916.1 RP11-1029M24.1 NDUFB1P1 FCF1P2 RP11-24C3.2 RP11-1029M24.4 RN7SL321P VPS26BP1 RN7SL664P RNU7-128P Y_RNA MIR4443 MIR2115 AC124916.2 SNRPFP4 MRPS18AP1 ZNF652P1 RP11-646D13.1 AC144634.1 ST13P14

UC 4q24

chr4:102467408-103091883

rs3774959

NFKB1 MANBA

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
4q24	chr4:102467408-103091883	rs3774959 G>A	3.66e-12^C	1.12 (1.08-1.16)^C	A	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs3774959 G>A	UC	024	3.66e-12^C	1.12 (1.08-1.16)^C	A

Genes

Protein-coding Genes UBE2D3 MANBA SLC9B1 BDH2 SLC9B2 NFKB1 CISD2
Non-coding Genes AF213884.3 LRRC37A15P RNU7-151P KRT8P46 AF224669.3 RP11-10L12.2 AC083826.1 ACTR3BP4 AF213884.2 RP11-10L12.1 PABPC1P7 RP11-10L12.4
Protein Coding Genes +/-0.5Mb of Region BANK1 SLC39A8 TACR3 CENPE
Non-coding Genes +/-0.5Mb of Region MTND5P5 RN7SL728P AF213884.1 RP11-498M5.2 AP002022.1 RP11-499E18.1 DDX3P3 RP11-297P16.4 RP11-328K4.1 RP11-297P16.3

UC 4q13.3

chr4:73859603-74142734

rs2472649

CXCL5 CXCL1 CXCL8 PF4V1 CXCL2 PF4 CXCL3 CXCL6

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
4q13.3	chr4:73859603-74142734	rs2472649 G>A	2.57e-08^C	1.12 (1.06-1.19)^C	G	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs2472649 G>A	IBD	017	4.15e-07^C	1.1 (1.04-1.15)^C	G
rs2472649 G>A	UC	024	2.57e-08^C	1.12 (1.06-1.19)^C	G

Genes

Protein-coding Genes CXCL3 CXCL2 PF4 CXCL5 MTHFD2L CXCL1 PPBP
Non-coding Genes HNRNPA1P55 RN7SL218P RP11-629B11.4 PPBPP2 CXCL1P
Protein Coding Genes +/-0.5Mb of Region AFP CXCL6 AFM ALB CXCL8 RASSF6 PF4V1 EPGN AREG EREG
Non-coding Genes +/-0.5Mb of Region PPBPP1 RP11-622A1.2 AC112518.3 RP11-447E20.1 RP11-622A1.1 AC142293.3 AC097470.1 RP11-629B11.5 RP11-727M10.1

UC 4q27

chr4:122017479-122644147

rs7657746 rs17388568

ADAD1 IL2 IL21

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
4q27	chr4:122041392-122644147	rs17388568 G>A	9.49e-07^D	1.12 (1.07-1.17)^D	A	029
4q27	chr4:122017479-122644147	rs7657746 A>G	1.79e-09^C	1.12 (1.09-1.18)^C	A	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs7657746	CRO		2.39e-09	1.09	A
rs7657746	UC		5.27e-10	1.10	A
rs17388568	CEL	009	2.74e-08	1.12	A
rs17388568	T1D	025	1.06e-09	1.13	A
rs7657746	IBD	017	9.52e-11	1.12	A
rs7657746	UC	024	8.33e-09	1.13	A
rs17388568 G>A	T1D	005	3.27e-06^D	1.26 (1.11-1.42)^D	A
rs17388568 G>A	T1D	039	2.94e-04^C	1.27 (1.15-1.39)^D	A
rs17388568 G>A	UC	029	9.49e-07^D	1.12 (1.07-1.17)^D	A
rs7657746 A>G	CRO	021	1.01e-09^C	1.11 (1.06-1.15)^C	A

Genes

Protein-coding Genes KIAA1109 IL2 IL21 ADAD1
Non-coding Genes AC097533.1 RN7SL335P IL21-AS1
Protein Coding Genes +/-0.5Mb of Region TMEM155 CCNA2 EXOSC9 BBS7 ANXA5 TRPC3 FGF2 NUDT6 SPATA5 BBS12
Non-coding Genes +/-0.5Mb of Region RP11-63B13.1 PP12613 AC021205.1 CETN4P RP11-170N16.2 RP11-170N16.3 AC021205.2 RP11-170N16.1 AC109357.1

UC 5p15.2

chr5:10667329-10839728

rs267939

DAP

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5p15.2	chr5:10667329-10839728	rs267939 T>C	6.01e-12^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs267939 T>C	UC	029	6.01e-12^C

Genes

Protein-coding Genes DAP
Non-coding Genes CTD-2154B17.3 CTD-2154B17.1 CTD-2154B17.4 CTD-2154B17.2
Protein Coding Genes +/-0.5Mb of Region CCT5 ANKRD33B FAM173B CMBL MARCH6 ROPN1L CTNND2
Non-coding Genes +/-0.5Mb of Region CTD-2199O4.3 Y_RNA CTD-2256P15.2 LINC01513 CTD-2256P15.5 CTD-2256P15.3 RP11-54F2.1 CTD-2199O4.5 CTD-2199O4.6 CTD-2256P15.4 AC012640.1 RPL30P7 RP11-54F2.8 RP11-1C1.5 MIR6131 CTD-2199O4.4 RP11-1C1.6 RP11-54F2.9 ANKRD33B-AS1 RP11-215G15.4 RP11-1C1.4 CTD-2199O4.7 CTD-2256P15.1 Y_RNA ROPN1L-AS1 RNU6-429P

UC 5q31.3

chr5:142033064-142260854

rs6863411

NDFIP1 SPRY4

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5q31.3	chr5:142033064-142260854	rs6863411 T>A	9.87e-06^C	1.08 (1.03-1.11)^C	T	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs6863411	CRO	021	2.67e-08	1.10	T
rs6863411	CRO		1.87e-14	1.10	T
rs6863411 T>A	IBD	017	1.25e-12^C	1.09 (1.05-1.12)^C	T
rs6863411 T>A	UC	024	9.87e-06^C	1.08 (1.03-1.11)^C	T

Genes

Protein-coding Genes NDFIP1
Non-coding Genes CTC-463A16.1 AC005740.4
Protein Coding Genes +/-0.5Mb of Region GNPDA1 DIAPH1 ARAP3 RELL2 PCDH12 FCHSD1 HDAC3 PCDH1 RNF14 KIAA0141 SPRY4 FGF1
Non-coding Genes +/-0.5Mb of Region AC005753.1 AC005740.3 AC005740.6 AC008781.7 CTD-2024I7.1 AC005740.5 CTD-2024I7.13 AC005592.3 AC005215.1 SPRY4-IT1_2 SPRY4-IT1 AC005592.1 AC005592.2 SPRY4-IT1_1 RPS12P10

UC 5p15.33

chr5:490122-717906

rs11739663

EXOC3 SLC9A3

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5p15.33	chr5:490122-717906	rs11739663 T>C	1.81e-08^C	1.08 (1.03-1.11)^C	T	024
5p15.33	chr5:490122-717906	rs11739663 T>C	2.80e-08^D	1.15 (1.09-1.2)^D	T	029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs11739663 T>C	UC	029	2.80e-08^D	1.15 (1.09-1.2)^D	T
rs11739663 T>C	UC	024	1.81e-08^C	1.08 (1.03-1.11)^C	T

Genes

Protein-coding Genes SLC9A3 TPPP ZDHHC11B CEP72
Non-coding Genes MIR4456 RP11-310P5.2 RP11-310P5.1 CTD-2589H19.6
Protein Coding Genes +/-0.5Mb of Region PLEKHG4B PDCD6 AHRR SDHA LRRC14B EXOC3 CCDC127 NKD2 SLC6A19 BRD9 SLC12A7 ZDHHC11 TRIP13
Non-coding Genes +/-0.5Mb of Region CTD-2228K2.1 RP11-811I15.1 CTD-2083E4.5 CTD-2228K2.2 EXOC3-AS1 CTD-2083E4.7 AC021087.1 PP7080 CTD-2083E4.4 CTD-2231H16.1 Y_RNA CTD-2083E4.6 CTD-2228K2.7 RP11-43F13.4 CTD-3080P12.3 RP11-43F13.3 BRD9P2 SPCS2P3 MIR4635 RP11-661C8.2 RP11-661C8.3

UC 5q31.1

chr5:132075186-132658977

rs2188962

ACSL6 IL3 SLC22A4 SLC22A5 IL5 IL4 PDLIM4 IL13 IRF1 CSF2

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5q31.1	chr5:132075186-132658977	rs2188962 C>T	3.81e-09^C	1.08 (1.04-1.12)^C	T	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs2188962	CRO	021	2.30e-33	1.22	A
rs2188962 C>T	IBD	017	3.74e-37^C	1.16 (1.13-1.19)^C	T
rs2188962 C>T	UC	024	3.81e-09^C	1.08 (1.04-1.12)^C	T

Genes

Protein-coding Genes SLC22A4 CSF2 IRF1 IL13 C5orf56 P4HA2 PDLIM4 RAD50 SLC22A5 IL5
Non-coding Genes snoZ6 AC063976.2 AC063976.3 RP11-89G4.1 TH2LCRR MIR3936 AC063976.7 AC116366.6 AC063976.1 P4HA2-AS1 AC034220.3 Y_RNA AC116366.5
Protein Coding Genes +/-0.5Mb of Region FNIP1 CTB-127M13.1 RAPGEF6 MEIKIN CTC-432M15.3 ACSL6 IL3 CCNI2 SHROOM1 SOWAHA UQCRQ ZCCHC10 KIF3A LEAP2 IL4 SEPT8 HSPA4 GDF9 AFF4
Non-coding Genes +/-0.5Mb of Region AC005593.2 AC034228.2 AC034228.4 AC034228.3 AC004775.5 AC010240.2 Y_RNA RP11-485M7.2 AC004237.1 ATP6V0E1P1 CTC-350I8.1 RP11-485M7.3 RNA5SP192 Y_RNA AC010240.3 RP11-485M7.1

UC 5p13.1

chr5:40286865-40626651

rs11742570 rs6451493

PTGER4

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5p13.1	chr5:40286865-40626651	rs11742570 C>T	1.36e-10^C	1.08 (1.04-1.12)^C	C	024
5p13.1	chr5:40286865-40626651	rs6451493 T>G	2.80e-09^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs11742570	CRO		3.66e-87	1.28	G
rs11742570	MS	030	2.08e-08	1.10	G
rs11742570	CRO	021	1.72e-50	1.29	G
rs11742570 C>T	UC	024	1.36e-10^C	1.08 (1.04-1.12)^C	C
rs6451493 T>G	UC	029	2.80e-09^C
rs11742570 C>T	CRO	011	7.08e-36^D	1.33 (1.27-1.39)^D	C
rs11742570 C>T	IBD	017	3.46e-59^C	1.19 (1.16-1.23)^C	C

Genes

Protein-coding Genes
Non-coding Genes AC108105.1
Protein Coding Genes +/-0.5Mb of Region RPL37 C7 PTGER4 MROH2B CARD6 PRKAA1 AC008810.1 TTC33
Non-coding Genes +/-0.5Mb of Region GCSHP1 LINC00604 RNU1-150P KRT18P56 LINC00603 RNU7-161P SNORD72 SNORA57 RP11-301A5.2 SNORA63

UC 5q33.1

chr5:150658703-151012930

rs11741861

TNIP1 IRGM

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5q33.1	chr5:150658703-151012930	rs11741861 A>G	1.05e-07^C	1.15 (1.08-1.22)^C	G	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs11741861	CRO		5.88e-44	1.33	G
rs11741861	CRO	021	2.76e-22	1.32	G
rs11741861 A>G	IBD	017	2.31e-26^C	1.25 (1.19-1.31)^C	G
rs11741861 A>G	UC	024	1.05e-07^C	1.15 (1.08-1.22)^C	G

Genes

Protein-coding Genes SYNPO DCTN4 IRGM MYOZ3 ZNF300 RBM22 SMIM3
Non-coding Genes CTC-311G1.1 CTC-311G1.2 ZNF300P1 CTC-345K18.2
Protein Coding Genes +/-0.5Mb of Region CD74 ARSI CDX1 NDST1 TCOF1 RPS14 SLC6A7 CAMK2A SLC36A3 FAT2 GM2A SLC36A2 CCDC69 SLC36A1 GPX3 AC008641.1 ANXA6 TNIP1
Non-coding Genes +/-0.5Mb of Region CTB-140J7.2 CTC-367J11.1 AC011372.1 CTC-224D3.1 AC034205.1 CTB-23I7.3 CTB-17P3.4 CTC-251D13.1 CTB-23I7.1 CTB-23I7.2 RNA5SP197

UC 5p13.2

chr5:35795636-36035028

rs3194051

IL7R

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5p13.2	chr5:35795636-36035028	rs3194051 A>G	4.22e-08^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs3194051 A>G	UC	029	4.22e-08^C

Genes

Protein-coding Genes UGT3A1 CAPSL IL7R SPEF2 UGT3A2
Non-coding Genes RP11-79C6.3 RP11-79C6.1 RP11-79C6.2 CTD-2113L7.1
Protein Coding Genes +/-0.5Mb of Region SKP2 RANBP3L NADK2 LMBRD2
Non-coding Genes +/-0.5Mb of Region U3 RNU7-130P AC027347.1 MIR580 RNA5SP181 RNU6-1305P CTD-2197M16.1 NADK2-AS1

UC 5q35.3

chr5:177079730-177421018

rs12654812

DOK3

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5q35.3	chr5:177079730-177421018	rs12654812 G>A	6.67e-08^C	1.08 (1.04-1.11)^C	A	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs12654812 G>A	UC	024	6.67e-08^C	1.08 (1.04-1.11)^C	A
rs12654812 G>A	IBD	017	1.68e-08^C	1.07 (1.04-1.10)^C	A

Genes

Protein-coding Genes F12 RAB24 SLC34A1 FGFR4 MXD3 NSD1 PRELID1 LMAN2 PFN3 ZNF346 GRK6 RGS14
Non-coding Genes CTD-2301A4.3 PRMT1P1 CTD-2301A4.1
Protein Coding Genes +/-0.5Mb of Region UIMC1 EIF4E1B TSPAN17 GPRIN1 SNCB CDHR2 HK3 UNC5A DBN1 TMED9 FAM153A PRR7 FAM193B PDLIM7 B4GALT7 DDX41 DOK3
Non-coding Genes +/-0.5Mb of Region LINC01574 MIR4281 RP11-375B1.1 RP11-375B1.2 ZNF346-IT1 RP11-1334A24.6 RP11-1101H11.1 OR1X5P RP11-423H2.5 PRR7-AS1 RP11-1334A24.5 RP11-1026M7.2 RP11-423H2.1 RP11-1277A3.3 RP11-1277A3.2 AC106795.1 RP11-1277A3.1 RP11-1026M7.3

UC 5q31.1

chr5:135044841-135190861

rs254560

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5q31.1	chr5:135044841-135190861	rs254560 G>A	2.55e-09^C	1.06 (1.02-1.09)^C	A	024
5q31.1	chr5:135044841-135190861	rs254560 G>A	1.25e-09^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs254560 G>A	IBD	017	1.54e-08^C	1.04 (1.01-1.07)^C	A
rs254560 G>A	UC	024	2.55e-09^C	1.06 (1.02-1.09)^C	A
rs254560 G>A	UC	029	1.25e-09^C

Genes

Protein-coding Genes
Non-coding Genes CTC-276P9.2 C5orf66 CTC-276P9.3
Protein Coding Genes +/-0.5Mb of Region CAMLG SAR1B SEC24A PITX1 C5orf24 TXNDC15 CATSPER3 DDX46 JADE2 PCBD2 H2AFY NEUROG1 DCANP1 TIFAB CXCL14
Non-coding Genes +/-0.5Mb of Region AC006077.3 MTND5P11 MTND4LP30 C5orf66-AS1 AC006077.4 CTC-276P9.4 RNU6-757P RNU6-1311P RNU6-1164P CTB-2L9.1 MTCYBP18 MTND6P4 MTND4P12 MTND3P25 MIR4461 CTB-138E5.1 CTC-203F4.2 C5orf66-AS2 CTC-321K16.1 CTC-321K16.4

UC 5q33.3

chr5:159397971-159460964

rs6871626

IL12B

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
5q33.3	chr5:159397971-159460964	rs6871626 C>A	2.39e-22^C	1.15 (1.11-1.20)^C	A	024
5q33.3	chr5:159397971-159460964	rs6871626 C>A	1.11e-21^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs6871626	IBD	017	8.82e-28	1.18	A
rs6871626	CRO	021	2.09e-26	1.20	A
rs6871626	UC	024	1.69e-14	1.15	A
rs6871626 C>A	AS	026	3.10e-08^C	1.10^C	A
rs6871626 C>A	UC	029	1.11e-21^C

Genes

Protein-coding Genes
Non-coding Genes AC008697.1 AC008703.1
Protein Coding Genes +/-0.5Mb of Region IL12B EBF1 RNF145 UBLCP1 ADRA1B
Non-coding Genes +/-0.5Mb of Region SNORA68 RNU4ATAC2P CTD-2363C16.1 RP11-175K6.2 AC011376.1 CTD-2363C16.2 CTB-11I22.1 RP11-175K6.1 CTB-11I22.2 AC008703.2 GAPDHP40 AC008691.1 AC011343.1

UC MHC

chr6:32371299-32715138

rs6927022 rs9268853

HLA-DRB5 HLA-DRA HLA-DRB1 BTNL2 HLA-DQA1 HLA-DQB1 HLA-DQA2

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
MHC	chr6:32371299-32684804	rs9268853 T>C	1.35e-55^D	1.41 (1.33-1.47)^D	T	029
MHC	chr6:32426760-32715138	rs6927022 A>G	4.71e-133^C	1.45 (1.39-1.49)^C	A	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs9268853	CEL	009	1.19e-59	1.41	T
rs6927022 A>G	UC	024	4.71e-133^C	1.45 (1.39-1.49)^C	A
rs6927022 A>G	IBD	017	3.19e-52^C	1.14 (1.1-1.18)^C	A
rs9268853 T>C	UC	029	1.35e-55^D	1.41 (1.33-1.47)^D	T

Genes

Protein-coding Genes HLA-DRA HLA-DRB1 HLA-DQB1 HLA-DRB5 C6orf10 HLA-DQA1 BTNL2
Non-coding Genes MTCO3P1 HLA-DQB1-AS1 HLA-DRB6 RNU1-61P HLA-DRB9 HCG23
Protein Coding Genes +/-0.5Mb of Region NELFE C4B C4A AL645922.1 STK19 AGER CFB SLC44A4 DXO CYP21A2 TNXB SKIV2L RNF5 AGPAT1 EGFL8 PPT2-EGFL8 PRRT1 C2 GPSM3 PBX2 NOTCH4 PPT2 ATF6B ZBTB12 FKBPL XXbac-BPG116M5.17 EHMT2 HSD17B8 SLC39A7 HLA-DOB RXRB TAP1 TAP2 BRD2 HLA-DMA HLA-DOA HLA-DPA1 RING1 COL11A2 HLA-DQB2 HLA-DQA2 PSMB9 XXbac-BPG181M17.5 XXbac-BPG246D15.9 HLA-DPB1 HLA-DMB PSMB8
Non-coding Genes +/-0.5Mb of Region C4B-AS1 RNU6-603P XXbac-BPG154L12.5 XXbac-BPG154L12.4 CYP21A1P EHMT2-AS1 RNA5SP206 MIR1236 XXbac-BPG300A18.13 HNRNPA1P2 MIR6833 C4A-AS1 TNXA STK19B MIR6721 C2-AS1 PPP1R2P1 HLA-DPA2 XXbac-BPG181M17.6 RNY4P10 HLA-DPA3 PSMB8-AS1 HLA-DPB2 MIR219A1 HLA-DQB3 MIR3135B AL645941.1 COL11A2P1 HCG24 XXbac-BPG254F23.7 RPL32P1 BRD2-IT1 HLA-Z

UC 6q23.3

chr6:137568592-137806067

rs6920220

TNFAIP3

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
6q23.3	chr6:137568592-137806067	rs6920220 G>A	1.40e-21^C	1.16 (1.11-1.21)^C	A	024
6q23.3	chr6:137568592-137806067	rs6920220 G>A	8.05e-17^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs6920220	UC	024	5.19e-12	1.16	A
rs6920220	IBD	017	4.78e-08	1.10	A
rs6920220 G>A	RA	019	2.30e-13^C	1.20^C	A
rs6920220 G>A	T1D	040	7.26e-06^D	1.12^D	A
rs6920220 G>A	RA	005	1.58e-05^D	1.20 (1.06-1.36)^D	A
rs6920220 G>A	UC	029	8.05e-17^C
rs6920220 G>A	SLE	015	4.00e-07^C	1.17 (1.10-1.25)^C	A
rs6920220 G>A	T1D	025	7.26e-06^D	1.12^D	A

Genes

Protein-coding Genes
Non-coding Genes RP11-95M15.1 RP11-356I2.1 AL357060.1 RP11-95M15.2 Y_RNA
Protein Coding Genes +/-0.5Mb of Region OLIG3 IFNGR1 IL22RA2 PBOV1 PERP ARFGEF3 TNFAIP3
Non-coding Genes +/-0.5Mb of Region BTF3L4P3 RPSAP42 RP11-356I2.4 RP11-240M16.1 RP11-10J5.1

UC 6q21

chr6:111075054-111647042

rs3851228

TRAF3IP2 FYN REV3L

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
6q21	chr6:111075054-111647042	rs3851228 A>T	1.77e-11^C	1.18 (1.10-1.26)^C	T	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs3851228	UC		1.13e-14	1.20	A
rs3851228	CRO		2.76e-08	1.14	A
rs3851228 A>T	IBD	017	1.08e-13^C	1.15 (1.09-1.22)^C	T
rs3851228 A>T	CRO	021	4.02e-07^C	1.14 (1.07-1.21)^C	T
rs3851228 A>T	UC	024	1.77e-11^C	1.18 (1.10-1.26)^C	T

Genes

Protein-coding Genes SLC16A10 KIAA1919 TRAF3IP2 REV3L
Non-coding Genes BRD7P4 RP5-1112D6.8 C6orf3 REV3L-IT1 TRAF3IP2-AS1 RP11-428F8.2 RP5-1112D6.4 FCF1P5 RP3-415N12.1 RNU6-960P RP5-1112D6.7
Protein Coding Genes +/-0.5Mb of Region GTF3C6 CDK19 RPF2 AMD1 TUBE1 FAM229B WISP3 LAMA4 FYN
Non-coding Genes +/-0.5Mb of Region RP11-346C16.6 RNU6-906P RNU6-1115P RP11-346C16.1 RP11-569A2.2 CNN2P9 RP3-418A9.3 RP11-397G5.2 RP11-346C16.2 AL357515.1 SNORA40 GSTM2P1 RNU6-957P AL158035.1 RP1-97J1.2

UC 6q21

chr6:105954686-106115679

rs6568421 rs6911490

PRDM1

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
6q21	chr6:105954686-106099497	rs6568421 A>G	6.22e-06^C	1.07 (1.03-1.11)^C	G	024
6q21	chr6:105959511-106115679	rs6911490 C>T	1.01e-08^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs6568421 A>G	IBD	017	2.52e-17^C	1.11 (1.07-1.14)^C	G
rs6911490 C>T	UC	029	1.01e-08^C
rs6568421 A>G	CRO	011	4.37e-08^D	1.13 (1.07-1.18)^D	G
rs6568421 A>G	UC	024	6.22e-06^C	1.07 (1.03-1.11)^C	G
rs6568421 A>G	CRO	021	8.24e-20^C	1.14 (1.10-1.18)^C	G

Genes

Protein-coding Genes PRDM1
Non-coding Genes RP1-134E15.3
Protein Coding Genes +/-0.5Mb of Region AIM1 ATG5 RTN4IP1
Non-coding Genes +/-0.5Mb of Region RP3-359N14.2 RP3-359N14.1 RN7SKP211 Y_RNA RP3-335E1.1 Y_RNA RNA5SP211 RNU6-344P RP11-404H14.1 RN7SL47P U4 RNU6-527P

UC 6p23

chr6:14691381-14736360

rs17119

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
6p23	chr6:14691381-14736360	rs17119 A>G	9.37e-07^C	1.05 (1.01-1.11)^C	A	024

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs17119 A>G	IBD	017	3.08e-11^C	1.08 (1.03-1.11)^C	A
rs17119 A>G	UC	024	9.37e-07^C	1.05 (1.01-1.11)^C	A
rs17119 A>G	CRO	021	8.51e-09^C	1.08 (1.04-1.12)^C	A
rs17119 A>G	MS	030	1.00e-10^C	1.11^D	A

Genes

Protein-coding Genes
Non-coding Genes RP11-146I2.1
Protein Coding Genes +/-0.5Mb of Region
Non-coding Genes +/-0.5Mb of Region RP11-330A16.1 RP3-448I9.2 LINC01108 RNU6-793P RP3-448I9.1 RP11-359N11.1 RP1-190J20.2 RN7SL332P AL050335.1

UC 6p21.1

chr6:43803265-43855043

rs943072

Hits

Chr Band	Position	Marker	P Value	OR (95% CI)	Risk Allele	Study
6p21.1	chr6:43803265-43855043	rs943072 T>G	2.37e-10^C			029

Markers

Marker	Disease	Study	P Value	OR (95% CI)	Risk Allele
rs943072 T&g