Overview

IDAllelesLocationGenome BuildSource
rs6498114G/Tchr16: 1087026138dbsnp146
rs6498114G/T chr16: 10964118 37dbsnp146_grch37
rs6498114T/G chr16: 10870261 38ImmunoChip
rs6498114T/G chr16: 10964118 37ImmunoChip
rs6498114T/G chr16: 10871619 36ImmunoChip

Jbrowse

Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs61259009rs6498114rs6498114130

Criteria

rs6498114 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs6498114 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  CIITA 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs6498114, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.