IDAllelesLocationGenome BuildSource
rs4675374T/Cchr2: 20393785538dbsnp146
rs4675374T/C chr2: 204802578 37dbsnp146_grch37
imm_2_204510823T/C chr2: 203937855 38ImmunoChip
imm_2_204510823T/C chr2: 204802578 37ImmunoChip
imm_2_204510823T/C chr2: 204510823 36ImmunoChip


Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build


rs4675374 meets the following criteria:

Criteria Name
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs4675374 as derived from dbSNP:
  • in intron
  • in 5prime utr
Gene(s) at location of variation:  ICOS 


Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).



Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs4675374, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.