Overview

IDAllelesLocationGenome BuildSource
rs3135394A/Gchr6: 3244072038dbsnp146
rs3135394A/G chr6: 32408497 37dbsnp146_grch37

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs114573742rs3135394rs3135394137
rs386580143rs3135394rs3135394142

Criteria

rs3135394 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 
Marker is in r2>0.8 with an index SNP 

Functional Information

Gene function properties for rs3135394 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  HLA-DRA 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs3135394, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.