Overview

IDAllelesLocationGenome BuildSource
rs1860545G/Achr12: 633761138dbsnp146
rs1860545G/A chr12: 6446777 37dbsnp146_grch37
imm_12_6317038T/C chr12: 6337611 38ImmunoChip
imm_12_6317038T/C chr12: 6446777 37ImmunoChip
imm_12_6317038T/C chr12: 6317038 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs117027064rs1860545rs1860545132
rs56741758rs1860545rs1860545130

Criteria

rs1860545 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is in r2>0.8 with an index SNP 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs1860545 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  TNFRSF1A 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs1860545, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.