Overview

IDAllelesLocationGenome BuildSource
rs180515A/Gchr17: 5994691438dbsnp146
rs180515A/G chr17: 58024275 37dbsnp146_grch37
rs180515A/G chr17: 59946914 38ImmunoChip
rs180515A/G chr17: 58024275 37ImmunoChip
rs180515A/G chr17: 55379057 36ImmunoChip

Jbrowse

Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs16943965rs180515rs180515123
rs56819533rs180515rs180515130
rs3169806rs180515rs180515106

Criteria

rs180515 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs180515 as derived from dbSNP:
  • in intron
  • in 3prime utr
Gene(s) at location of variation:  RPS6KB1 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs180515, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.