Overview

IDAllelesLocationGenome BuildSource
rs12720356A/Cchr19: 1035929938dbsnp146
rs12720356A/C chr19: 10469975 37dbsnp146_grch37
rs12720356T/G chr19: 10359299 38ImmunoChip
rs12720356T/G chr19: 10469975 37ImmunoChip
rs12720356T/G chr19: 10330975 36ImmunoChip
imm_19_10330975T/G chr19: 10359299 38ImmunoChip
imm_19_10330975T/G chr19: 10469975 37ImmunoChip
imm_19_10330975T/G chr19: 10330975 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs386525782rs12720356rs12720356142
rs61473256rs12720356rs12720356130

Criteria

rs12720356 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is an index SNP in a Region 
Marker is GW-Significant in a Study 

Functional Information

Gene function properties for rs12720356 as derived from dbSNP:
  • has reference
  • has non-synonymous missense
Gene(s) at location of variation:  TYK2 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs12720356, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.