Overview

IDAllelesLocationGenome BuildSource
rs1250546A/Gchr10: 7927277538dbsnp146
rs1250546A/G chr10: 81032532 37dbsnp146_grch37
imm_10_80702538A/G chr10: 79272775 38ImmunoChip
imm_10_80702538A/G chr10: 81032532 37ImmunoChip
imm_10_80702538A/G chr10: 80702538 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build

Criteria

rs1250546 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs1250546 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  ZMIZ1 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs1250546, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.