Overview

IDAllelesLocationGenome BuildSource
rs12445568T/Cchr16: 3099349138dbsnp146
rs12445568T/C chr16: 31004812 37dbsnp146_grch37
imm_16_30912313T/C chr16: 30993491 38ImmunoChip
imm_16_30912313T/C chr16: 31004812 37ImmunoChip
imm_16_30912313T/C chr16: 30912313 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs58174069rs12445568rs12445568130

Criteria

rs12445568 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs12445568 as derived from dbSNP:
  • in intron
Gene(s) at location of variation:  STX1B 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs12445568, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.