Overview

IDAllelesLocationGenome BuildSource
rs1059312A/Gchr12: 12879431938dbsnp146
rs1059312A/G chr12: 129278864 37dbsnp146_grch37
imm_12_127844817A/G chr12: 128794319 38ImmunoChip
imm_12_127844817A/G chr12: 129278864 37ImmunoChip
imm_12_127844817A/G chr12: 127844817 36ImmunoChip

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Historical Ids

Old Marker IDNew Marker IDCurrent Marker IDdbSNP Build
rs3741612rs1059312rs1059312108
rs118202097rs1059312rs1059312142
rs3199981rs1059312rs1059312106
rs17433701rs1059312rs1059312126
rs58588632rs1059312rs1059312130

Criteria

rs1059312 meets the following criteria:

Criteria Name
Details
Disease Tags
Marker is GW-Significant in a Study 
Marker is an index SNP in a Region 

Functional Information

Gene function properties for rs1059312 as derived from dbSNP:
  • has synonymous
  • has reference
Gene(s) at location of variation:  SLC15A4 

Study

Studies containing regions of association that span this marker are shown below. Please note that when making comparisons across studies, that they may vary in terms of size, genotyping platform, and exclusion criteria. If the 'Odds Ratio' is less than 1 then the region is protective (alleles are marked as blue) otherwise it is susceptible (alleles marked as red).

StudyPublicationDiseaseRegionMarkerAllelesP-valueORMAFGene(s)

Populations

Populations data from Ensembl 1000 Genome data release May 2013:

Linkage Disequilibrium Statistics

LD Search Options

Linkage disequilibrium (LD) statistics are calculated for rs1059312, using the 1000 genomes data release May 2013. Calculations are performed with the snpStats R library, covering 1Mb either side of the marker; and with the following filters applied: MAF > 0.01, call rate < 0.9, and chi-squared test for deviation from HWE > 25.